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Pharmaceutics
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SYNTHESIS, SPECTROSCOPIC, THERMAL AND BIOLOGICAL ASPECTS OF NICKEL(II) COMPLEXES WITH HYDANTOIN


Abstract

Author(s): Vikas A. Desai, Priyank P. Mistry, Bhadresh R. Sudani

A series of organic hydantoin-compounds containing Nickel as an inorganic element for enhancing the pharmacological activity was synthesized. They have been characterized by elemental analysis, (FT-IR, 1H &13 C NMR, and electronic) spectra, magnetic measurements and thermal studies. A magnetic moment and reflectance spectral study reveals that an octahedral geometry has been assigned to all the prepared complexes. Ligands (Ln) and their metal complexes were screened for their in-vitro antimicrobial activity against some microorganisms. The results showed some lower to moderate activities.

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Citations : 440

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