Abstract
Author(s): Sabry Khalil* 1,2, Hanan Farag3
Ion-associate complexes of Selegiline hydrochloride; Sg HCl with [Co (II), Mn (II) thiocyanates], potassium ferricyanide and
ammonium reineckate are precipitated. The solubility of the solid complexes at the recommended optimum conditions of pH and
ionic strength values have been studied. Saturated solutions of each ion associate at different temperatures under the optimum
precipitation conditions were prepared and the metal ion contents in the supernatant were determined. A new accurate and precise
method based on inductively coupled plasma atomic emission spectrometry for the micro-determination of Selegiline hydrochloride
(0.45-49.22 μg/ml) in pure solutions, pharmaceutical formulations and urine samples is given.
