Abstract
Author(s): Anjali A Mali*, Vishnu Vasant Mali and Prashant Shamkuwar
Topical film forming system is a novel approach for treatment of skin diseases give both topical and transdermal treatment. Rate and extent of drug absorbed through skin depends on the physiology of skin and properties of drug. FFS is defined as non-solid doses form which produces film in situ i.e., on the evaporation of vehicle, excipients in the formulations form film on skin. These are mainly drug and film forming polymers. Film forming system formulations consist of spray, solution, gel, and emulsion. Formed film acts as a matrix for sustained release of drug and it also improves the patient compliance. It can provide some desirable performance over conventional pharmaceutical dosage formulation such as easily applied, improve drug delivery, reduce dose frequency, omitted first pass effect, and enhance drug delivery. Various hydrophilic and hydrophobic polymers are used to give desired film properties, used either single or in combination with two or more polymers.
