Abstract
Author(s): P. Sivakumar*1, Anil Ahuja 2, T. Venkatachalm3
Tuberculosis (TB) is an infectious disease caused by Mycobacterium Tuberculosis, is the second leading infectious cause of death in world. The aim of this study was to evaluate the ADRs to anti tubercular drugs in tuberculosis patients. It was prospective observational study 300 patients were included and were monitored for ADRs. Out of 300 patients, 110 (36.66%) developed ADR. The incidence of ADRs were found to be more in females (77.27%) as compared to males (22.72%). Incidence of ADRs were maximum in the age group 21-40 years (63.63%). Majority of ADRs were Increased liver enzyme transaminase (23.12%) and followed by gastritis (19.90%). As a pharmacist we have the liability to support the patients during the period of antitubercular treatment. These ADR may steer the patient to make a judgment for stopping the medications and finally the occurrence of drug resistance and an amplified health care cost. If a proper educational system is implemented, most of the patient may report their ADR and thereby we can improve the patient adherence and therapeutic outcome.
